- A Case of Successful Treatment for Recurrent Hepatocellular Carcinoma with Long term Survival
-
Jin Hyoung Lee, Ja Kyung Kim, Hwa Sook Kim, Sang Hoon Ahn, Chae Yoon Chon, Young Myoung Moon, Kwang-Hyub Han, Woo Jung Lee, Young Nyun Park, Seung Hyoung Kim, Kwang Hoon Lee, Do Yun Lee, Jong Tae Lee
-
Journal of the Korean Liver Cancer Study Group. 2006;6(1):20-24. Published online June 30, 2006
-
-
-
Abstract
PDF
- The long term results of surgery for hepatocelluar carcinoma are not satisfactory, because the high incidence
of intrahepatic tumor recurrence, with a 5-year acturial recurrence rate of 75% to 100%. The risk factors for
postoperative recurrence such as venous invasion, presence of satellite nodules, large tumor size, advanced TNM
stages are the best-established. For the management of postoperative recurrence, studies largely focused on the
recurrence in the remnant liver. The therapeutic modalities commonly used for surgical resection, TACE,
percutaneous ethanol injection (PEIT), and systemic chemotherapy. We report a case of recurrent hepatocellular
carcinoma after curative resection, successfully treated by TACE, TACI, and systemic chemotherapy with long
term survival.
- Fever, Thrombocytopenia and the Deterioration of Liver Function after Open Surgical Radiofrequency Ablation Therapy
-
Jae Gil Lee, Suk Mo Kim, Kyung Sik Kim, Jong Yoon Won, Nae Chun Yoo, Dong Sup Yoon, Jin Sub Choi, Woo Jung Lee, Byong Ro Kim
-
Journal of the Korean Liver Cancer Study Group. 2005;5(1):71-74. Published online June 30, 2005
-
-
-
Abstract
PDF
- The surgical resection is the only curative modality for hepatocellular carcinoma (HCC); however the surgical
approach is limited by residual function of liver and multiplicity of tumor. The radiofrequency ablation (RFA) is
introduced recently as a therapeutic modality, an alternative to percutaneous ethanol injection therapy (PEIT) for
HCC. The advantages of open surgical RFA include better cancer staging with open intraoperative ultrasound, the
availability of an intraoperative ultrasound guide system, the accessibility to tumors in all areas of the liver,
avoidance of adjacent organ injury, the ability to perform hepatic inflow occlusion which reduces the heat-sink
effect, and the possibility of combining RFA with hepatic resection. The complications after open surgical
radiofrequency ablation are rarely reported.
A 59 year old man with fever, thrombocytopenia and the deterioration of liver function after open surgical RFA
was experienced. The patient’s hepatic function was given a Child-Pugh score of A6 points and the value of ICG
R15 test was 55.2%. The open surgical RFA was performed on the S2, S3, S4 and S8. Although the patient was
fully recovered without sequelae by conservative managements, the inclusion criteria have to be established
carefully through following reviews on clinical results after open surgical RFA.
|